INTEGRATIVE GENOME-SCALE ANALYSES REVEAL POST-TRANSCRIPTIONAL SIGNATURES OF EARLY HUMAN SMALL INTESTINAL DEVELOPMENT IN A DIRECTED DIFFERENTIATION ORGANOID MODEL

Abstract Background MicroRNAs (miRNAs) are important post-transcriptional gene regulators controlling cellular lineage specification and differentiation during embryonic development, including the gastrointestinal system.However, miRNA-mediated regulatory mechanisms involved in early embryonic development of human small intestine (SI) remains under

Abstract Theanine (Thea) is a unique metabolite in tea plants, but its physiological functions remain elusive.A low soil pH increases cadmium ealisboa.com (Cd) availability, affecting the quality of tea plant products.In this study, we found that Thea reversed the Cd-induced reduction in free amino acid (FAA) and caffeine (CAF) in the young tea lea